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RESULTS DATA

POPULATION STRATIFICATION

Specific codon biases and genes that were the most statistically different between populations.

Codon Frequency

Subpopulation:

Gene	Isoform	Codon	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	GCA	61.2%	< 5x10^-324	14.3881
		ACA	60.9%	< 5x10^-324	14.3881
		N/A
ACKR1	NP_001116423.1	GGT	55.1%	9.3113x10^-222	6.5841
		GAT	55.1%	9.3113x10^-222	6.5841
		GCA	8.31%	2.0305x10^-15	0.8031
ZNF646	NP_055514.3	GGG	55.4%	3.7014x10^-209	6.2204
		GAG	53.8%	6.3742x10^-207	5.8005
		GAA	52.3%	7.0106x10^-158	4.4430

Superpopulation:

Gene	Isoform	Codon	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	GCA	80%	< 5x10^-324	4.5975
		ACA	80%	< 5x10^-324	4.5975
		N/A
ACKR1	NP_001116423.1	GGT	90%	< 5x10^-324	4.4389
		GAT	90%	< 5x10^-324	4.4132
		GCA	70%	6.026x10^-58	0.6904
ZNF646	NP_055514.3	GGG	80%	< 5x10^-324	3.5180
		GAG	80%	< 5x10^-324	3.4961
		GAA	80%	< 5x10^-324	3.0178

Co-tRNA Codon Pairing

Subpopulation:

Gene	Isoform	Amino Acid	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	Thr	61.8%	< 5x10^-324	14.3881
		N/A
		N/A
ACKR1	NP_001116423.1	Gly	56.3%	9.3113x10^-222	6.5841
		Asp	56.3%	9.3113x10^-222	6.5841
		Ala	9.54%	2.0305x10^-15	0.8031
SLC30A9	NP_006336.3	Val	46.2%	1.1197x10^-177	5.0771
		N/A
		N/A

Superpopulation:

Gene	Isoform	Amino Acid	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	Thr	80%	< 5x10^-324	4.5447
		N/A
		N/A
ACKR1	NP_001116423.1	Gly	90%	< 5x10^-324	4.4388
		Asp	90%	< 5x10^-324	4.4132
		Ala	70%	2.1159x01^-56	0.6803
AHSA1	NP_036243.1	Leu	70%	< 5x10^-324	3.3035
		Val	40%	5.3397x10^-41	0.5717
		N/A

Identical Codon Pairing

Subpopulation:

Gene	Isoform	Codon	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	GCA	61.2%	< 5x10^-324	14.3881
		N/A
		N/A
ACKR1	NP_001116423.1	GAT	55.1%	9.3113x10^-222	6.5841
		N/A
		N/A
ZNF646	NP_055514.3	GGG	55.7%	3.7014x10^-209	6.2204
		GAG	53.2%	2.6925x10^-205	5.7429
		ACT	42.2%	2.5272x10^-89	2.5849

Superpopulation:

Gene	Isoform	Codon	% Significant Population Comparisons	Min P-Value	Max Effect Size
SLC24A5	NP_995322.1	GCA	80%	< 5x10^-324	4.5975
		N/A
		N/A
ACKR1	NP_001116423.1	GAT	90%	< 5x10^-324	4.4388
		TTC	30%	1.3887x10^-28	0.4700
		N/A
ZNF646	NP_055514.3	GGG	80%	< 5x10^-324	3.5380
		GAG	80%	< 5x10^-324	3.3803
		GCA	90%	2.8240x10^-236	1.6980

Ramp Sequences

Subpopulation:

Gene	Isoform	% Significant Population Comparisons	Min P-Value	Max Effect Size
ACSM2A	NP_001295098.1	8.31%	3.7312x10^-268	5.6807x10¹⁴
PACRG	NP_689623.2	1.85%	3.6664x10^-130	4.2093x10¹⁴
EHMT2	NP_079532.5	22.8%	< 5x10^-324	1.0830x10¹⁴

Superpopulation:

Gene	Isoform	% Significant Population Comparisons	Min P-Value	Max Effect Size
NUDT7	NP_001230590.1	10%	6.9725x10^-193	8.5616x10⁷
ACSM2A	NP_001295098.1	40%	1.0230x10^-33	91810.9778
CBLC	NP_036248.3	10%	9.2220x10^-51	3631.9351

DATA

Data Files

Click on a file to download it.

Satistically Significant Population Differences Data Files:

codon_frequency_sub.csv
codon_frequency_super.csv
co_trna_sub.csv
co_trna_super.csv
identical_sub.csv
identical_super.csv
ramp_sub.csv
ramp_super.csv

Scripts: